Evaluation of serum LDH levels in patients with suspected sepsis and its relation to outcome of disease

Abstract

Myoglobin is a heterodimer compound that consists of a peptide chain and a group. Sepsis is a set of systemic inflammatory responses to infection that cause harmful effects on the human body. The aim of this study was to evaluate the changes in myoglobin and its effect on the severity and outcome of sepsis in Imam Reza Hospital in Tabriz. Materials & Methods: In this study, patients were divided into three categories: sepsis, severe sepsis and septic shock. Were also compared and examined. Also, blood culture was performed from all patients included in the study and the results were evaluated for gram-positive or gram-negative. Results: There was no significant difference between the three groups in terms of age (P = 0.59) and heart rate (P = 0.18). While in terms of myoglobin in all 4 times (P = 0.00), hospitalization days (P = 0.01), fever (P = 0.00) and SOFA (P = 0.00) were significantly different so that with increasing sepsis severity of this rate Variables increased. There was no significant difference in the sex distribution ratio between the groups (p> 0.05). The highest rate of involvement in each group of patients is related to the respiratory department. Patients' outcome (survival / death) in different groups were significantly different (p = 0.00). Higher percentage of Gram-negative implantation result and frequency of implantation result were not significantly different between different groups. (p.value = 0.86)