Evaluation of the relationship between diuresis and kidney function in transplant patients of Tabriz Imam Reza Hospital

Abstract

Nowadays, kidney transplantation is the method of choice and cost-effective treatment for ESRD patients, which has significantly reduced mortality and complications of the disease. In this study, we intend to investigate the effects of diuresis on kidney function in transplant patients. The aim of this cross-sectional analysis is to find out the relationship between kidney function and the diuresis in patients undergoing kidney transplantation. Methods: This cross-sectional study was performed on kidney transplant patients of Imam Reza Medical Center in Tabriz. In this study, patients were evaluated based on inclusion and exclusion criteria. Demographic information of patients including age, gender, underlying Hypertension of the patients were recorded. In this study, the eGFR of patients was calculated by the formula (GFR with MDRD equation) and its relationship with the rate of recovery urinary output and 3-hour urinary output was calculated. Results: 49 patients who underwent kidney transplant surgery participated in this study. The results of this study indicated that among the laboratory parameters of patients including preoperative sodium, preoperative potassium, preoperative urea, postoperative sodium, postoperative potassium, postoperative urea, postoperative creatinine, there was no significant relationship. In addition, no relationship between postoperative GFR and patients' diuresis in the recovery room and 24 hours after surgery was showed. Also, there was no significant relationship between indicators such as age and the rate of diuresis of patients in the recovery room and within 24 hours after surgery. This study could not determine a significant difference in preoperative GFR, postoperative GFR, recovery output, 24-hour output between patients with hypertension and the group without hypertension. Furthermore, this study did not show a significant difference between diuresis volume in patients with GFR ≥ 30 and GFR <30.