Assessment of LV systolic function before and after percutaneous balloon mitral valvulotomy in patients with stenotic mitral valve

Abstract

Mitral stenosis is a common cause of valvular heart disease in developing countries. It causes an increase in left atrial pressure and pulmonary artery pressure. However, the left ventricle is usually demonstrating normal size and function among these patients in conventional echocardiographic studies. Percutaneous Transvenous Mitral Commissurotomy (PTMC) is the treatment of choice for this condition. The aim of this study was to evaluate the changes in left ventricular systolic function before and after PTMC among patients with mitral stenosis using conventional and 2D strain echocardiography.

Materials and Methods: This cross-sectional study was performed on patients with mitral stenosis who underwent PTMC at Shahid Madani Hospital of Tabriz University of Medical Sciences. Strain echocardiography was performed on patients before and one month following PTMC. These results were compared and analyzed regarding the LA and LV function of the studied participants before and after the procedure.

Results: In this study, 26 patients were enrolled. Of which 73% were female and 27% were male. The mean age of the patients was 56.88±9.9 years. The mean mitral valve area of studied individuals before and after PTMC was 1.12 ± 0.21 and 1.87±0.12 cm2, respectively. LVEF of patients did not change statistically significantly before and after PTMC. Regarding the strain echocardiography values, in all evaluated parameters (GLS, GCS, LAVi) the changes after PTMC were statistically significant (P <0.001).