| dc.description.abstract | This study aimed to evaluate the association between endometrial pathologies with incidental abnormal sonographic findings of endometrium in postmenopausal women.
Materials and Methods: In this analytical cross-sectional study, the target population were those who underwent trans-abdominal and vaginal ultrasonography of the uterus for reasons other than uterine bleeding, referring to Al-Zahra Teaching Hospital of Tabriz University of Medical Sciences. Among the eligible women, 86 women consented to undergo intrauterine sampling and pap-smear if intra-uterine fluid or endometrial thickening (above 5 mm) was detected. Histopathology results were recorded. IBM SPSS (26) was used for examining the hypothesized associations. A p-value of 5% or lower is considered to be statistically significant.
Results: The median age of the patients was 55 years, IQR: [51-60]. The most common chief complaint of patients at the time of referral was pain (54.65%), of which abdominal pain was the most frequent type. Of these, 20.93% of patients came in for annual gynecological control. Among those with endometrial thickening (above 5 mm), endometrial thickness between 5 and 8 mm, comprised 41.86% of the samples, which was the most common sonographic finding. Pearson's correlation analysis did not show a relationship between endometrial thickness with age or patients' BMI (p=0.183 and p=0.386; respectively). Pap smear results reported "no-pathology" in 73.25% of participants, Squamous Cell carcinoma in 1(%). Other pap-smear were reported to have inflammation. There is no statistically significant relationship between endometrial thickness and endometrial biopsy pathology findings (X (27)=36.49; p=0.105). The most common finding in endometrial biopsies was atrophic endometrium (34.88%), accompanied by polyps in 2.33% of patients. The second common finding was the presence of polyps, which had a frequency of 15.15%. Normal pathology was reported in 16.28% of patients. No statistically significant relationship was observed between Pap smear results and pathology of endometrial biopsy (X(63)=78.86; p=0.146). In patients with endometrial thickness greater than 8 mm, there were 11 cases (23.4%) of polyps, and 9 cases (19.1%) of abnormal endometrial proliferation. Polyps with endometrial proliferation were also observed in 2 cases. | en_US |
