Choroidal thickness in non-alcoholic fatty liver disease

Abstract

The choroid has the highest blood flow in the body and is one of the most common sites involved in systemic diseases such as malignancies. Non-alcoholic fatty liver disease is one of the most common causes of chronic liver diseases and its most important cause is obesity. This disease is one of the most important causes of morbidity and mortality in the world. Studying thickness of choroid in different diseases, can help us in diagnosis and follow-up of these diseases. Method: Data of 25 patients with non-alcoholic fatty liver disease and 20 normal patients were extracted and they were matched by age and sex. Then, ocular examinations were performed and the choroid thickness was measured in the subfoveal, 500 and 1000 μm distance from nasal and temporal sides by EDI-OCT method. SPSS software version 23 and Mann Whitney U statistical test were used to analyze data. The study was conducted as a pilot. Results: In this study, the thickness of the choroid layer of eye was examined in 5 areas, including the subfoveal, 500 and 1000 μm nasal and temporal side. Based on these findings, there was no significant difference between choroid thickness in different areas in patients and normal individuals.