Correlation of urinary potassium and acute kidney injury in patients admitted to intensive care unit

Abstract

Acute kidney injury (AKI) is a prevalent disorder in the intensive care unit (ICU) and so far there is no good way to predict the progression of AKI and patients’ prognosis. Researchers have for a long time sought to use urinary markers as a rapid testing method to help manage oliguria and AKI. The aim of the current study is to determine the role of urinary potassium and creatinine clearance on prediction of AKI in critically ill patients. Methods and Materials: All patients who were hospitalized in the ICU of Shohada Hospital from January 2020 to January 2021 and had a urinary catheter were included in this study. Patients with a history of previous AKI, anuria or a history of dialysis were excluded from the study. In all patients, 2 hour urine samples were acquired on the first day of hospitalization along with blood samples; and were tested for e sodium, potassium and creatinine. All cases were followed within 10 days in terms of complications, maximum serum creatinine, need for dialysis, AKI and mortality. Data were analyzed using Spss Ver 22 software. Results: In this study, 201 patients were examined. AKI has been reported in 91 cases (45.3%). Mortality was reported in 32 patients (9.15%). Cr (Plasma) / K (urine), Clearance Cr / K (urine) factors were higher in stage I AKI, and no AKI than stage II AKI, respectively. Na (Urine) / K (Urine) factor was higher respectively in stage II

AKI, and then in stage I AKI, than patients without AKI. Na (urine), K (urine), Na (urine) / K (plasma), Cr / K clearance (urine), and urine (volume) / K (urine) clearance in dead patients was significantly lower than alive patients. Na (Urine) / K (Urine) factor in the event of death, was significantly higher than alive patients.