Long Term Follow up of Pediatric Patients with Celiac Disease

Abstract

The aim of this study was to find the effective factors in the development of growth retardation and non-response to diet in mania in celiac patients. . method: Out of 382 patients with suspected celiac disease, biopsy of the duodenum was performed in the gastrointestinal tract of Tabriz Children's Hospital and 93 patients with positive pathology were included in the study regardless of the antibody and genetic titer and their demographic information was recorded and analyzed. Results; The mean age of people (19-2) was 9.41 + 3.41 and 35 (37.6%) were boys and 58 (61.4%) were girls. The incidence of underweight was 17.1% in boys and17.2% in girls The incidence of short stature was 14.3% in boys and 13.8% in girls. At less than 5 years of age, more growth disorders were observed than in other age groups. The percentage of improvement in short stature was significantly better in children with higher marching and responded better to the treatment regimen.(Pvalue=0.04 ). People with comorbidities had higher AntiTTG antibody titers and lower Hb levels were more likely to have growth retardation and failure to respond to treatment. Eleven (11.8%) people had a positive family history. People in the first degree family had celiac disease. They had less growth disorder than others. The most common complaints reported by patients were abdominal pain 54(40% ) and diarrhea 39(28% ). 62 patients (77%) had typical celiac disease, 15 patients (16%) had atypical type celiac disease, but growth retardation and lack of response to treatment were more common in patients with atypical type. 26.7% underweight and short stature in atypical celiac Equivalent to 15.7% underweight and 11.4% short stature in typical celiac disease.