The Association Between Serum Levels of 25(OH)D3 and Dry Eye Syndrome

Abstract

The aim of this study was to determine the level of serum vitamin D in patients with dry eye. materials and methods. After approval by the Regional Committee on Bioethics of Human Research, the objectives of the study were explained to all participants who were selected according to the inclusion and exclusion criteria, and after obtaining informed consent, entered the study. After completing the OSDI questionnaire, patients were divided into three groups with mild, moderate and severe dry eye based on the questionnaire classification. Serum levels of vitamin D were measured for all participants in the study. Results. In the present study, 80 patients who presented with dry eye and 80 in the control group were included in the study and the serum level of vitamin D in patients with dry eye was 25.68 ± 8.54 units per ml and in the control group 33.44 ± 12.80 units per milliliter and this difference was statistically significant (P <0.001). Although the serum level of vitamin D in men with dry eye was 27.51 ± 8.07 units per ml and in women with dry eye was 24.46 ± 8.70 units per ml, but this difference was not statistically significant. (P=0.113). The mean serum level of vitamin D in the 20 to 40 years age group is 22.15 ± 7.16 units per ml, in the 40 to 60 age group is 26.60 ± 9.16 units per ml and in people over 60 years was 27.92 ± 8.19 units per ml, which was also statistically significant (P = 0.043).