The association of lymphocytes to neutrophils and lymphocytes to platelet ratio with ST segment resolution following primary angioplasty in acute ST-elevation myocardial infarction

Abstract

One of the most prominent inflammatory markers that have been taken into consideration in the prognosis of myocardial infarction is the reduction in the number of lymphocytes in the peripheral blood. The aim of this study was to evaluate the relationship between the ratio of lymphocyte to neutrophil and lymphocyte to platelet resolution with ST segment following PTCA in patients with STEMI. Materials and Methods: In this study 218 patients with acute myocardial infarction were included in the study. Demographic variables and CBC results were recorded at the hospital entrance. The cardiovascular stroke taken in the emergency room before coronary angiography as well as the cardiac arrhythmia from patients were examined for 90 minutes after PTCA in the CCU and the rate of ST segment drop in the lids that had an ST segment elevation was evaluated by the cardiologist Researcher) was evaluated. Patients who had had at least 50% ST drop after 90 minutes of treatment were considered as patients who did not respond appropriately. Results: The results of this study indicate that there is a direct and significant relationship between LNR and LPR with ST segment resolution. The results of linear regression analysis and t-test showed that with increasing LNR and LPR values, ST segment resolution was higher and the patient had better outcomes. The LNR in ST resolutions was equal to and above 50% equal to 0.68 ± 0.66 and in the resolutions below 50% was 0.33 ± 0.32. The mean ± standard deviation of LPR in ST resolutions was equal to and higher than 50%, equal to 0.0780 ± 0.0069 and in the resolutions below 50%, was 0.104 ± 0.0055.