Estimation of familial risk of genetic and congenital diseases in the northwest of Tabriz

Abstract

Despite improvements in the health and medical status, genetic and congenital anomalies are responsible for many prenatal and neonatal mortalities in many countries. These anomalies have an important role in disturbing the health of the infants and children. The present study aimed to create an online system at primary prevention to estimate familial risk of genetic and congenital diseases. Methods: In this cross-sectional and descriptive study, the March of Dimes questionnaire of family health before and after pregnancy was used to collect data .The questionnaire was completed by the study subjects after an interview with them and explaining the different parts of the questionnaire. All the subjects signed informed consent forms. The data were analyzed with the Excel software. The data were categorized in four groups: no risk, low risk, moderate risk, and high risk. Results: According to the results, 91.2% of the subjects (95%CI: 88.4–93.9) were placed in the no risk group; only 1% of the subjects (95%CI: 0.02–1.9) were placed in the high risk group. The majority of subjects in the no risk group were 19–25 years of age (42.85%, 95%CI: 33.6–52). In addition, the majority of the subjects in the no risk group had no previous child. Besides, none of the subjects in the no risk, moderate risk, and high risk groups had a history of toxoplasmosis.