Relationship between Red Blood Cell Distribution Width, Neutrophil to Lymphocyte Ratio and Neutrophil to Platelet Ratio with Intracranial Hemorrhage 3 months Prognosis

Abstract

Red blood cell distribution (RDW) is a parameter that indicates the heterogeneity of red blood cell size. Recent studies have shown that this parameter in addition to hematological diseases such as anemia in some diseases such as ischemic strokes And increased cardiovascular disease and can be used as a prognostic factor. And since intracerebral hemorrhage is considered a vascular event with a high mortality rate. We also undertook a study to evaluate the relationship between three factors of blood elements. (RDW, NLR: Neutrophil lymphocyte ratio, NPR: Neutrophil platelet ratio) with a 3-month prognosis of intracranial hemorrhage. Materials & Methods: This cohort study was a retrospective cohort study performed on 140 randomly selected patients with intracranial hemorrhage admitted to the neurology ward of Imam Reza Hospital in Tabriz. Underlying diseases and test results of the first 24 hours after admission as well as NIHSS of patients at the time of admission and 28-day mortality and status of patients three months after discharge (recorded in data collection forms). Results: In 140 patients evaluated, the mean age was 61.14 years with a standard deviation of 16, of which 51% were male and 49% were female. Hypertension with 75.7% was the most underlying disease and hyperlipidemia with 5% was the least underlying disease. RDW variable had a significant positive correlation with neutrophil, hemoglobin and RBC variables and a negative negative correlation with MCHC variable. 90%) There was a significant difference between the group of patients who died and recovered after 3 months. In the results of logistic regression to predict the quarterly prognosis of patients, RDW and NIHSS variables were significant in patients' death.