Distribution of breast density in screening mammography and its association with breast cancer risk factor

Abstract

Breast cancer is one of the most common cancers worldwide and also in Iran. Despite advances in the role of genetic and biochemical markers for its early detection. The aim of the present study was to evaluate the density of breast tissue in Tabriz population and its relation with breast cancer risk factors. Materials and Methods: In this cross-sectional study, a one-year study of eligible women referred to Alzahra Hospital for screening was performed and a questionnaire containing demographic variables including age, anthropometric variables such as BMI and related variables was used. Fertility and hormone intake, such as menstrual age, birth control pills, menstrual status, lactation, number of children, time of menopause and breast size, are completed and evaluated in patients undergoing mammography. Results: The mean age of the patients was 45.68±6.96 years with a mean age of 44.5 years. The population of women with a breast density above 50% was higher than that of a low breast density (51.4% vs. 48.6%). In women without a history of breast-feeding, the prevalence of breast density was greater than 50% in 76.4% of women. The highest frequency was related to cup breast size 85 with frequency of 104 cases (29.7%). The highest frequency was of Type B with a frequency of 154 cases (44%) and then Type C with a frequency of 152 cases (43.4%). Significantly lower densities were observed at the time of menopause and at higher densities at the time of non-menopause (p=0.001).