A comparison of the Sevoflurane and Isoflurane Anesthesia on the quality of recovery after outpatient pediatric surgery with laryngeal mask

Abstract

Induction and maintenance of general anesthesia in children is often administered by inhalation anesthesia. Which should provide rapid induction, haemodynamic stability, analgesia and amnesia. Sevoflurane is a good anesthetic used in pediatric outpatient surgery because of its low odor and low solubility in blood and tissues. On the other hand, the low solubility of isoflurane (blood-gas partition coefficient equals 1.4) enables a rapid induction of and recovery from anesthesia so the present study was conducted to compare inhalational anesthesia recovery with sevoflurane and isoflurane in pediatric outpatient surgeries in order to use the best anesthesia technique for children. Methods: Children aged 2 months to 6 years old undergoing outpatient surgery were randomly assigned to one of two groups of isoflurane (ISO) and receiving sevoflurane (SVO). Both groups were equally anesthetized with fentanyl, midazolam, lidocaine, propofol. An appropriately sized LMA was implanted And maintenance of anesthesia Was performed with isoflurane (0.5-2 vol.%) And souflurane (2-3 vol.%). In this study demographic characteristics, awakening quality in recovery, hemodynamic status, and other complications such as patient agitation, pain, nausea, and vomiting were evaluated in both groups. Results: Patients did not differ significantly in terms of demographic characteristics. Incidence of postoperative agitation and shivering was higher in the sevoflurane group than the isoflurane group. The highest percentage of pain was obtained as 52.5% in the sevoflurane group. Patients in the sevoflurane group experienced nausea and vomiting more frequently than patients in isoflurane group (%15 vs %5), there was a significant decrease in the heart rate of the subjects in the (Svo) group as one of hemodynamic variables (P = 0.001).