| dc.description.abstract | The aim of this study is to comparison of pathologic differences in adenoid tissues of allergic patients with non-allergic patients.
Materials and Methods: In this descriptive study, 50 patients with allergic adenotonsil hypertrophy were selected as candidates for surgery according to standard criteria by an allergist. An ENT specialist was referred and 50 patients with non-allergic adenotonsil hypertrophy were selected as candidates for surgery by the nasopharynx and sent to the grooming room. Samples were sent to the pathology department from the operating room, which was placed in a formalin fixative solution. Then they underwent tonsillectomy by a specialist and then tonsil samples were compared in patients with allergic and non-allergic adenotonsillar hypertrophy in terms of pathology, number of eosinophil, lymphocytes, neutrophils and the presence or absence of lipids.
Results: In this study, the mean (standard deviation) age of the two groups of patients with allergic and non-allergic adenotonsillar hypertrophy was 7.48 (±2.3) and 6.80 (±2.6) years, respectively. Also, in the two groups of patients (allergic and non-allergic adenotonsillar hypertrophy) the mean (SD) of eosinophil count was 16.44 (±6.0) and 18.02 (±6.3), lymphocyte counts was 7.48 (±1.4) and 5.84 (±2.4), neutrophil counts was 10.72 (±2.9) and 15.93 (±2.8), and the presence of lipids was 18 cases (48.6%) and 19 cases (51.4%), respectively. Among all the studied variables, family history of asthma and allergic rhinitis, history of asthma and allergic rhinitis in the patient, positive result of prick test (air allergen, food and mite) and lymphocyte count were significantly more in patients with allergic adenotonsillar hypertrophy than in patients with non-allergic adenotonsillar hypertrophy and neutrophil count was significantly more in patients with non-allergic adenotonsillar hypertrophy than in patients with allergic adenotonsillar hypertrophy (P-value <0.001); While in other variables such as: eosinophil count, presence of lipids, gender, age, family history of tonsillitis, smoking in the family, the large degree of pharyngeal and third tonsil, how to diagnose, sleep apnea, persistent night snoring and continuous open mouth breathing, there was no statistically significant difference between the two groups (P-value> 0.05). | en_US |
