Etiology, prognosis, risk factors and antibiotic resistance pattern of isolated pathogens in children with Bacteremia

Abstract

The aim of this study was to determine the frequency, prognosis, risk factors and antibiotic resistance pattern in children with bacteremia. Materials and Methods: This was a descriptive cross-sectional study between September 2013 and September 2018.In our study, 204 children with positive blood culture who are admitted toTabriz Children's Hospital, were investigated. We gathered information through analysis of patient records and a questionnaire prepared for this purpose. Results: In this study, 112 persons (52/8%) were male and 92 persons (47/2%) were female. Gram positive blood cultures were more common than gram negative ones (62/3% vs 37/7%) and coagulase negative staphylococci (39/2%) was the most common isolated microorganism and Klebsiella(10/8%) was in the second place. Toatal mortality rate was 29/3%. The risk factors which found for bacteremia in this study were surgery procedures in 37/7%, preterm being (in neonatals) in 22/6%, presence of localized infection in 18/6%, and immunosuppression state in 5/4% of cases. Gram positives were largely resistant to Erythromycin(80/95%) and penicillin (78/5%) and had the most sensitivity to chloramphenicol (88/08%) and vancomycin (83/2%). But gram negatives had the most resistance to Cefixime (87/69%) and the most sensitivity to Imipenem (56/25%).