The effect of vitamin B complex administration on pain and sensory problems following implant replacements surgery on the posterior mandible

Abstract

Introduction: Inferior alveolar nerve damage can lead to mild to complete numbness and even facial pain. One of the treatments that is considered today for the reconstruction and treatment of damaged peripheral nerves is the use of vitamin supplements. The aim of this study was to evaluate the effect of vitamin B complex supplementation on pain and sensory problems following implant placement surgery behind the mandible. materials and methods: In this single-blind clinical trial study, 46 patients applying for implant placement who were eligible for the study were studied. All patients were examined for sensory facial injury and inferior alveolar nerve injury within 24 hours after implant placement. The effect of nerve damage was recorded by AI (asymmetry Index) in the initial examination. Patients who reported signs of nerve damage and showed clinical and radiographic signs of nerve damage due to implant or instrumental intrusion into the neural canal were excluded from the study and promptly treated with anti-inflammatory protocols. Then patients were randomly divided into control (n = 23) and intervention (n = 23) groups. Patients in the control group received routine treatment after implantation and patients in the intervention group received vitamin B complex pills in addition to routine treatment. A placebo was used to eliminate the inductive effect of the drug in the control group. Follow-up of patients was performed at intervals of 14 days, 1, 3, 2 months after treatment. Data analysis was performed using SPSS software version 24 and Kruskal-Wallis, Wilcoxon and Chi-square tests. Results: In both groups, a decreasing trend in pain intensity was observed for up to three months. There was no significant difference between the mean pain intensity in the intervention and control groups at all follow-up times. In both groups, a decrease in the rate of numbness was observed during the three months of follow-up. The mean of numbness in the two groups was not significantly different in any of the follow-up times. Conclusion : Vitamin B complex had no effect on reducing the severity of pain and numbness after implant surgery.