Determination of the level of Brain natriuretic peptide in the differentiation of transudative and exudative pleural effusion

Abstract

Given that the measurement of light criteria requires a laboratory check of fluid pleurisy and laboratory evaluations should be able to accurately diagnose the disease as soon as possible, and if the diagnostic power of BNP is observed to differentiate transvaginal and exudative pleural effusion, An early diagnosis was made by checking the substance in the patient's serum. Materials and Methods: This cross-sectional descriptive study was performed during 2019 in two hospitals of Imam Reza and Shohada (General ICU) with the participation of 100 patients with pleural effusion. Serum NT-proBNP levels of serum and fluid pleurisy were measured and compared on etiology between exudative and transudative groups in SPSS 20 statistical software with chi-square and t-test statistical tests at a significance level of less than 0.05. Results: NT-proBNP levels in serum(P=0/063) and pleural (P=0/100) fluid of patients with exudative pleural effusion and transudative pleural effusion were not statistically significant. Etiological studies have shown that NT-proBNP is significantly higher in both pleural fluid (P=0.01) and serum (P=0.029) in patients with comorbidities, both in fluid and fluid. Pleurisy was significantly higher in both serum and heart failure patients than in other patients.