Evaluation of deep tonsillar crypt microflora in allergic and non-allergic patients

Abstract

The aim of this study is to evaluation of deep and surface tonsillar crypt microflora in allergic and non-allergic patients. Materials and Methods: In this cross-sectional study, 50 patients with allergic adenotonsilar hypertrophy were selected as candidates for surgery according to standard criteria by an allergies specialist.Perrick test was performed for patients.if positive it was divided into three groups(aeroallergen,dietary,mite) and referred to ENT specialist. and 50 patients with non-allergic adenotonsilar hypertrophy were selected by the ENT specialist.They were sent to the operating room,for patients a questionnaire was prepared in the operating room,their demographic information was completed.then they underwent tonsillectomy by the specialist.samples from the deep and surface tonsilar crypts of all selected patients were taken and separately were entered into the culture medium proposed by the pathologist( Chocolate agar culture media and McConkey culture media). samples were transferred to the pathology unit of the hospital and the results were collected and analyzed and compared with each other. Results: In this study, the mean (standard deviation) age of the two groups of patients with allergic and non-allergic adenotonsillar hypertrophy was 7.48 (±2.3) and 6.80 (±2.6) years, respectively. The highest frequency of culture both on the surface and depth, in both groups of patients with allergic and non-allergic adenotonsillar hypertrophy was related to Staphylococcus aureus with 36 cases (0.72%) and 30 cases (0.60%), respectively. Among all the studied variables, variables of family history of asthma and allergic rhinitis, history of asthma and allergic rhinitis in the patient and positive result of prick test (air allergen, food and mite) were significantly more in patients with allergic adenotonsillar hypertrophy than in patients with non-allergic adenotonsillar hypertrophy (P-value <0.001); While in other variables such as: Result of culture (surface and depth), gender, age, family history of tonsillitis, smoking in the family, the large degree of pharyngeal and third tonsil, how to diagnose, sleep apnea, persistent night snoring and continuous open mouth breathing, there was no statistically significant difference between the two groups of patients with allergic and non-allergic adenotonsillar hypertrophy (P-value> 0.05).