Pregnancy Outcome in Mothers with Meconium Stained Amniotic Fluid in Educational Centers of Tabriz University of Medical Sciences in 2002 -2003.

Abstract

Abstract: Introduction: Meconium is the first defection of fetus and neonate. Intrauterine passage of meconium may represent normal physiologic or pathologic event. The presence of meconium stained amniotic fluid (MSAF) is relatively common and occurs in 5 -15% of births. Studies have showed that MSAF may be affected on maternal and neonatal outcome, however the risks associated with meconium stating remains uncertain and controversial. Materials & Methods: A retrospective analytic descriptive study done in Al –Zahra and Taleghani educational centers in Tabriz. We studied 8512 records of delivered women and selected 640 records which had criteria of investigation, in two groups of case and control (320 records with MSAF as case group and 320 records with clear amniotic fluid as control group). Our questionnaire consisted of 4 part: 1-demographic data, 2 –amniotic fluid status, 3 –maternal outcome, 4 –neonatal outcome. Data were then gathered and analyzed using SPSS9 software, by t, X2 tests. Results: The prevalence of MSAF in this study was 9.6% and the incidence of meconium aspiration syndrome was 3.8%. Thick meconium was presented in 232 (72.5%) infants. In addition there were statistically significant difference between maternal age (p=0.032), abnormal fetal heart rate (p=0.002), fetal sex (p=0.033), the 5th minute Apgar score (p=0.011), gestational age, mode of delivery, the first minute Apgar score, respiratory distress, postpartum cares, resuscitation and hospital stay days (p<0.001) in two groups. But there were no statistically significant differences in parity, induction of labor, birth weight and seizure in first 24h between two groups. Conclusions: According to this study meconium stained amniotic fluid is a predictor for some of adverse maternal and neonatal outcome.