Vitamin D deficiency role in atrial fibrillation following heart surgeries: systematic review

Abstract

This systematic review and meta-analysis of the observational studies aimed at evaluating the association between preoperative vitamin D deficiency and Postoperative atrial fibrillation. Materials and Methods: In this study, using PubMed, Scopus, Google Scholar, EMBASE, Web of Science, and Cochrane Libraries, we searched for records published before July 2020. Results: Two reviewers screened for studies that examined the relationship between preoperative vitamin D levels and the generation of POAF. Data regarding study design, patient characteristics, definition of AF, type of surgery, vitamin D levels, and measurement methods were extracted. 5 studies were included in the meta-analysis. Our primary analysis showed a significant relationship between preoperative levels of vitamin D and POAF development (MD: -2.851, 95% CI: -5.506 to -0.195; p-Value 0.035).