Comparison of salivary vitamin D in patients with chronic periodontit and healthy subjects

Abstract

Introduction: Chronic periodontitis is an inflammatory disease, one of the impotant sign is attachment loss of gingival and periodontal fibers. Studies show that vitamin D can affect periodontal conditions and its concentration is associated with chronic periodontitis. Vitamin D causes homeostasis of calcium and phosphorus in the body, and its deficiency causes the breakdown of bone mineral structure. Considering that all the studies have been prepared from the serum of patients with chronic periodontitis and no study has been done on the level of salivary vitamin D in these patients and also the preparation of saliva is morally non-invasive and desirable compared to the preparation of their serum. Therefore, this study was designed and performed to evaluate the level of vitamin D in the saliva of these patients. Methods and Materials: In this case-control study, salivary samples were taken from 50 patients with chronic periodontitis and 50 periodontally healthy individuals referred to the Department of Oral Diseases of the School of Dentistry from July 1999 to August 1999, using ELISA method And Hangzhou Kit (made in Korea) Salivary vitamin D levels were measured The results were analyzed using independent t-test and the software used in this study was SPSS.16 and P value less than 0.05 was considered significant. Results: The mean concentration of vitamin D in the patient group was 10.32 and in the healthy group was 11.08 and also the standard deviation was 3.12 in the patient group and 3.36 in the healthy group. The mean concentrations of vitamin D in men and women were also compared and it was found that there was no statistically significant difference between healthy and sick people in terms of salivary vitamin D in any of them. Conclusion: The results of this study showed that there was no significant difference between the mean salivary vitamin D levels in these patients and periodontically healthy individuals.