| dc.description.abstract | The aim of this study was to investigate the incidence of myositis and neuropathy concomitant with lupus among patients with SLE referred to the Electrodiagnosis Center of Physical Medicine and Rehabilitation clinic of Imam Reza Hospital in Tabriz.
Materials and Methods:
In a cross sectional study, patients with SLE who have been admitted in the rheumatology inpatient service and complained of hands or feet numbness, paresthesia or weakness were referred to electrodignosis center of rehabilitation clinic for performing nerve conduction study and needle electromyography during the past 3 year were selected. The incidence of neuroapthies and myoapthies among lupus patients, their electrodiagnostic pattern, involved muscles, severity of disorder, the occurrence of each kind of the neuroapthies and myopathies and its relationship with age and sex and duration of the disease were determined.
Results:
In this study, out of total 127 SLE patients, 45 cases were referred for electrodiagnosis and among them 32 patients had abnormal and 13 patients had normal EDX. 87.5% of patients were female and 12.5% were male. The mean age was 40.45 ± 14.13 years old. In this study, 28(22%) patients had myopathy, including 10(35.71%) cases of inactive dispersed myositis, 8 (28.57%) cases of polymyositis, 6(21.42%) cases of corticosteroid myopathy and 4 (14%) cases of active patchy myositis. Of the 17 (13% of total) neuropathic cases, the highest percentage of neuropathy was related to sural or median mononuropathy with a frequency of 8 (47.04%), sensorimotor polyneuropathy in 5 (29%) and mononeuritis multiplex in 4 (23%) of cases, respectively. The study also looked at fibrillation in different types of myopathies, in which active dispersed myositis and polymyositis both produced the most fibrillations and steroid induced myopathy caused the least fibrillation. No significant association was found between electrodegnostic findings and age or sex. However,significant correlation between incidence of polyneuropathy and age was noted. | en_US |
