The effect of age and sex on the histopathologic features of odontogenic cysts in patients referred to Tabriz dental school at 1387 until 1397

Abstract

Introduction: Proper diagnosis of oral and maxillofacial cysts is essential because a number of these lesions are aggressive and have a high recurrence rate. The aim of this study was to investigate the histopathological characteristics of different types of odontogenic cysts and its relationship with age and sex.

Materials and methods:

In this cross-sectional descriptive study, all pathological specimens that were diagnosed with maxillofacial cysts during the period 2008-2009 in Tabriz Dental School were examined. Clinical information was recorded according to patients' records. All H&E slides related to patients were extracted from the pathology file of the pathology department of the hospital and reviewed according to the latest WHO classification. Neville classification was used to examine the histopathological appearance of the lesions. For each cyst, the number of layers, depth of inflammation, type of inflammation, and severity of inflammation in the cyst wall were assessed. Results were reported as frequency and frequency percentage, mean ± standard deviation. SPSS / 20 software was used for data analysis

Results: In this study, 44 pathological specimens were examined with the diagnosis of maxillary cysts. The most common cysts were keratocyst with 38.6% and radicular cyst with 31.8%. The prevalence was 59.1% in men and 40.9% in women. Keratocyst cysts were similar in men and women. Radicular, residual and dentigros were more common in men than women. Periodontal lateral cysts were observed only in women. The highest prevalence was in the age group of 21-30 years and included keratocyst, radicular and residual. The lowest prevalence was in the age group of 50-41 and included keratocyst, residual, dentigerous and lateral periodontal. The highest mean number of layers was related to keratocyst and residual cysts. Residual cysts had the highest severity of inflammation, dentigerous cysts and lateral periodontal cysts had the highest type of inflammation (acute) and lateral periodontal cysts had the highest depth of inflammation.

Conclusion: Histopathologically, odontogenic cysts are associated with age and sex.