The evalution effective drugs for treatment of Non-alcohol Fatty Liver: a systematic review and meta-analysis

Abstract

Non-alcoholic fatty liver (NAFL) and steatohepatitis (NASH) are two forms of fatty liver disease, the former being benign and the latter malignant and lead to liver cirrhosis and in some cases hepatocellular carcinoma. Considering the importance of this disease and its high prevalence, further studies are needed. Is to summarize the results of various studies in this field and provide a clear vision for guaranteed or effective remedies.Method & Material:In this systematic search of sources identified 741 articles. 92 articles were duplicated, and 617 excluded after reviewing the title and review of the abstracts. After reviewing the full-text of articles, 19 articles were excluded. Finally, 6 articles that met the inclusion criteria were included in this meta-analysis study.Result:Based on ratings based on the score of therapeutic effects on NAS, it was found that treatment with Obet had the best change over NAS compared to the other drugs studied. The forest plot has also been shown to combine preliminary results in studies comparing grid meta-analysis compared with placebo treatment