The evaluation of effect of Platelet-Rich Plasma (PRP) in the treatment of patients with androgenic alopecia

Abstract

The objective of this clinical trial is evaluation of the effect of Platelet-Rich Plasma (PRP) in the treatment of patients with androgenic alopecia Methods: In this randomized clinical trial, 20 patients with androgenic alopecia referring to dermatology clinic of Sina hospital of Tabriz were assigned into the study. Interfollicular injection of Platelet-Rich Plasma (PRP), 0.1 ml/cm2 were performed 2 times in each patient in selected areas of the scalp at intervals of 30 days. The clinical manifestations and dermoscopy were used to evaluate the patients with androgenic alopecia. Before the intervention, 1 month, 3 months after the intervention were followed up respectively. Results: Twenty patients (16 males and 4 females) were examined. The mean age of the patients was 32.88 ± 1.3 and in range of 24 to 48 years. The results of this study showed a significant increase in the mean number of hair in treated areas in the third month compared with the beginning of the study. In the treated areas there was an average increase of 13.9 after first month and 33.6 hairs per cm2 after 3 months.