Show simple item record

dc.contributor.advisorNourie, Mohammad
dc.contributor.advisorhamdi, Kobra
dc.contributor.advisorAhmadi, Yadollah
dc.contributor.authorDaneshmandpour, Yousef
dc.date.accessioned2019-12-31T08:06:47Z
dc.date.available2019-12-31T08:06:47Z
dc.date.issued2019en_US
dc.identifier.urihttp://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/61214
dc.description.abstractMale infertility is one of the most prevalent Health problems around the globe which affcts millions of people. Evaluation of semen sample is most common used test for evaluation of male infertility but there is a significant overlap between semen parameters of fertile and infertile men which makes the charachtrization of male infertility difficult and the significate part of male infertility is called “unexplained infertility”. So, the researchers in the field of infertility tried to find new molecular markers for better characterization and understanding of male infertility. Material and methods: In current study sperm samples of 80 infertile male were recruited. 24 samples were asthemoteratospermia (AT), 18 asthenospermia (AS) and 17 numbers were Teratospermia (TS). 21 numner of semen samples were choosen to be normospermia (NS). Using Real-time PCR technique, expression level of three genes including UBE2B, CX3CR1 and SEMG1 were evaluated. Results: The current study indicated expression level of SEMG1 gene in all studied groups (AS, TS, AT) have been significantly altered, respectively. (p=0.047, p=0.027 and p=0.000). No significant alteration was observed in expression level of CX3CR1 gene compared to the control group. Also, using Real-time PCR no expression was observed in UBE2B gene in sperm samples.en_US
dc.language.isofaen_US
dc.publisherTabriz University of Medical Sciences, Faculty of Medicineen_US
dc.subjectMale infertilityen_US
dc.subjectAsthenospermiaen_US
dc.subjectAsthenoteratospermiaen_US
dc.subjectAsthenoteratospermiaen_US
dc.subjectteratospermien_US
dc.titleThe Analysis of expression level of UBE2B and CX3CR1 in sperm cell of infertile patientsen_US
dc.typeThesisen_US
dc.contributor.supervisorSakhinia, Ebrahim
dc.contributor.supervisorYousefi, Mehdi
dc.identifier.docno609372en_US
dc.identifier.callno9372en_US
dc.description.disciplineMedical Geneticsen_US
dc.description.degreeM. SC. Degreeen_US


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record