Evaluation of the effect of Chamomile flower extract on acne vulgaris

Abstract

Today the pharmaceutical industry is looking for effective ingredients with less complications and more adaptability to the body. Therefore, we have used chamomile flowers to accelerate the acne vulgaris skin disease. Targets The aim of this study was to determine the effect of Chamomile flower extract on acne vulgaris formulated as gel. Materials and Methods In a clinical study, 44 patients were randomly selected from those referring to the Sina Hospital of Tabriz who had mild to moderate acne vulgaris. Patients' information was obtained in two groups of control (group A: clindamycin gel 1%) and The intervention group (group B: clindamycin 1% gel composition and 2% chamomile gel) were studied. Results The rate of improvement of acne vulgaris inflammatory lesions was faster in group B but in the end there was no statistically significant difference between the two groups. Improvement of non-inflammatory lesions also had a very slow pace in group B than group A. There was no linear relationship between improvement and reduction of non-inflammatory lesions and there was no significant difference between the two groups. Patients' satisfaction after receiving treatment group A was 31.18% and in group B was 45.45%, which indicated the rate of recovery and satisfaction of patients in group B. Conclusion Therefore, it can be concluded that the medicinal gel of Chamomile extract (2% once daily) was effective in the treatment of acne vulgaris with mild to moderate severity. However, there was no statistically significant difference between the two groups, but the rate of improvement was significant and patients were more satisfied with the use of 1% solution of clindamycin alone