Evolution of serum and salivary level of creatinine and glucose in healthy people referring to Tabriz Dental School in 2018

Abstract

Introduction: Diabetes mellitus is a multifactorial metabolic disorder that affects various organs of the body. One of the most important resultant diseases is chronic kidney disease. Creatinine blood tests are the most common indication for the presence and progression of chronic kidney disease. As a result, serum creatinine is most commonly used to determine the presence and progression of chronic kidney disease. The purpose of this study was to determine the relationship between serum and salivary levels of creatinine and glucose in healthy subjects. Methods: This analytical study was performed on 40 healthy individuals referred to Tabriz Dentistry Faculty departments. Data were presented as mean (± standard deviation) and frequency (%) for quantitative and qualitative variables respectively. Data were analyzed by SPSS software version 19. Pearson / Spearman correlation coefficient was used to determine the correlation between the serum and salivary creatinine and glucose levels. P values less than 0.05 was considered significant. Results: Forty individuals participated in this study that 9 (22.5%) were male and 31 (77.5%) were female. The results showed that there was a significant difference between mean glucose and creatinine and there was a statistically significant difference between salivary and serum glucose and creatinine levels. There was no statistically significant correlation between salivary glucose and creatinine. Conclusion: The use of noninvasive diagnostic methods such as saliva has a great value. In this study, it was found that there was no relationship between serum creatinine and glucose and saliva in healthy individuals, so saliva cannot be used as a suitable diagnostic tool for screening and assessing the seemingly healthy people in the society.