Evaluation of Changes of Anthropometric Indices On Carotid Intima-Media Thickness in Patients with Non-Alcoholic Fatty Liver Disease

Abstract

Background: Non-alcoholic fatty liver disease (NAFLD) is a clinicohistopathological entity associated with obesity and has recently been reported as the most common form of chronic liver disease. NAFLD is used to describe a spectrum, from pure steatosis to steatohepatitis. The disease is associated with obesity, hypertension, dyslipidemia, type 2 diabetes mellitus and insulin resistance. Methods: the participants include all patients with NAFLD that refer togastroenterology clinics from 2007 to 2016. The sample size was 221 patients. Anthropometric data (weight, height and waist circumference) were measured. Carotid intima-media thickness (CIMT) was evaluated by ultrasound. All data were analyzed using SPSS (version 16). Results: A total of 221 adults with a median 45.2 ± 10.6 age (17 – 77 years old) with NAFLD were included in this cohort study. The study population consisted of 125 women (56.56%) and 96 (43.43%) men. Body mass index and right-CIMT, waist to height ratio and right and left-CIMT (PV = 0.005 and 0.025 respectively), and waist