Evaluation of 99mTc-GHA and 99mTc- DMSA scan's findings in diagnosis of renal cortical in suffering UTI patients

Abstract

This study introduces 99mTc-GHA radiopharmaceutical as a bifunctional renal radio-drug to provide renal scintigraphy with the possibility of further inspection of kidney membrane and function simultaneously. Methodology: In a descriptive-analytic study, all the patients with UTI, who had been referred to the nuclear medicine ward of Imam Reza Hospital by their doctors, were chosen by convenience sampling method. For a limited 5 patients both 99mTc-GHA and99mTc-DMSA scanning were done upon doctor's instruction and the results were compared. For the remaining patients, only 99mTc-GHA scan was administered and the renal cortex and function and the relevance to renal scars to GFR and creatinine were analyzed by SPSS 24 software. Results: Among the 21 patients affected with UTI,there were 11 females (52.4) and 10 males with respective average ages of 21.3±15.9 and 21.3±15.9 . The average renal GFR levels for the right kidney for patients with and without scars in the right kidney were respectively 25.57 ±11.90ml/min and 42.56±11.90ml/min Also, the average renal GFR levels for the left kidney for patients with and without scars in the left kidney were respectively 28.75±20.46ml/min and 43.15±20.51ml/min In addition, the average Creatinine level for patients with and without renal scars were respectively 1.64±0.72mg/DL and 1.0±53.42mg/DL.