The study of efficacy of Empagliflozin on metabolic effects of atypical antipsychotic drugs in patients with psychiatric disorders: a randomized clinical trial. Introduction: Antipsychotic medications are prescribed for ...

Introduction: It is important to receive multiple drugs and drug side effects and improper use of drugs in an arbitrary manner in the elderly. Purpose: to check the compliance of the medications received by elderly patients ...

Introduction: Antibiotic resistance is a major issue nowadays. Researchers have been looking for novel approaches to treat bacterial infections for several decades. Nisin, an antimicrobial peptide (AMP), can be thought of ...

Introduction: Cardiovascular diseases are one of the top 5 causes of death in the world today. So far, despite numerous clinical trials, no cure has been found for acute heart failure. The only way to treat heart failure ...

Introduction: Linagliptin and empagliflozin are among the new drugs in the treatment regimen of type 2 diabetes. These drugs play a significant role in controlling blood sugar and reducing the long-term complications of ...

Introduction: Oleuropein is a phenolic compound whose many applications as an antimicrobial agent in food are associated with problems such as degradation due to environmental conditions and unpleasant sensory characteristics, ...

Solubility is very important in the process of drug discovery and development. Solubility data provide important and useful information for the preparation of pharmaceutical formulations, the development of pharmaceutical ...

Considering the low¬ water solubility of most drugs, improving this feature is one of the important steps in drug research and development. One of the simplest and oldest methods of increasing solubility is cosolvency. In ...

Introduction: The main problem that follows the chronic use of opioids is the occurrence of dependence and tolerance. Morphine is a p-gp substrate. Clomipramine is a TCA that has inhibitory effects on p-gp. Aim: Evaluate ...

Introduction: According to the WHO database, cardiovascular disease (CVDs) is still the leading cause of mortality in the world. The prevalence of heart failure (HF) is increasing due to population aging. It has been ...