Comparison of serum and salivary level of creatinin and glucose in diabetic patients from october 2018 to september 2019 in Tabriz City

Abstract

Introduction: Diabetes is a multifactorial metabolic disease that can damage to different organs of body such as the kidneys, therefore considered as a major public health problem in many parts of the world and Iran. The aim of this study was to determine the relationship between serum and salivation levels of creatinine and glucose in patients with diabetes. Methods: This descriptive study was conducted on 40 patients with diabetes referred to Emam Reza Hospital and dental faculty. Data were presented mean (± standard deviation) and frequency (percentages) for quantitative and qualitative variables, respectively. Statistical analysis was performed by SPSS19 software. To compare the results and significant difference between them was used the Independent Samples T Test and Pearson correlation test. In this study, the significance level of P <0.05 was considered. Results: From 40 diabetic subjects we studied were 28 women and about 47% had literacy under the diploma. 45% of the people had hypertension. Except one, all of them had type II diabetes. In 36 cases, diabetes was controlled. Creatinine and glucose levels in serum were higher than saliva. There was not any relationship between precence or absence of hypertension and salivary glucose or creatinine levels. There was no significant correlation between serum and salivary creatinine, but there was a correlation between glucose in serum and saliva. Conclusion: It is important to measure accurately the factors affecting diabetics with the least damage to them. In this study, it was found that there is a positive relationship between glucose in saliva and blood in diabetic patients. In the future, salivary samples can be used to measure glucose in these individuals.