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Preparation and evaluation of toxicity of anti-epidermal growth factor receptor (EGFR) immunotoxin containing truncated Pseudomonas aeruginosa exotoxin-A and humanized single chain fragment variable

dc.contributor.advisorBarzegar, Abolfaz
dc.contributor.advisorRahmati, Mohammad
dc.contributor.advisorMahdieh, Nejat
dc.contributor.authorAkbari, Bahman
dc.date.accessioned2019-01-12T06:38:52Z
dc.date.available2019-01-12T06:38:52Z
dc.date.issued2016en_US
dc.identifier.urihttp://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/59560
dc.description.abstractThe results of this study indicated that huscFv-PE25 can recognize and pose inhibitory effect on EGFR-overexpressing cancer cells, despite its smaller size and lower immunogenicity. This may be providing a basis for development of novel clinical therapeutic agents against EGFR-overexpressing tumor cells.en_US
dc.language.isofaen_US
dc.publisherTabriz University of Medical Sciences Faculty of Advanced Medical Scienceen_US
dc.relation.isversionofhttp://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/59559en_US
dc.subjectE. colien_US
dc.subjectEGFRen_US
dc.subjectPseudomonas exotoxinen_US
dc.subjectImmunotoxinen_US
dc.subjectHumanized single chain antibodyen_US
dc.titlePreparation and evaluation of toxicity of anti-epidermal growth factor receptor (EGFR) immunotoxin containing truncated Pseudomonas aeruginosa exotoxin-A and humanized single chain fragment variableen_US
dc.typeThesisen_US
dc.contributor.supervisorFarajnia, Safar
dc.identifier.docno160en_US
dc.contributor.departmentMedical Biotechnologyen_US
dc.description.disciplineMedical Biotechnologyen_US
dc.description.degreePh.Den_US


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