Preparation and evaluation of toxicity of anti-epidermal growth factor receptor (EGFR) immunotoxin containing truncated Pseudomonas aeruginosa exotoxin-A and humanized single chain fragment variable

dc.contributor.advisor	Barzegar, Abolfaz
dc.contributor.advisor	Rahmati, Mohammad
dc.contributor.advisor	Mahdieh, Nejat
dc.contributor.author	Akbari, Bahman
dc.date.accessioned	2019-01-12T06:38:52Z
dc.date.available	2019-01-12T06:38:52Z
dc.date.issued	2016	en_US
dc.identifier.uri	http://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/59560
dc.description.abstract	The results of this study indicated that huscFv-PE25 can recognize and pose inhibitory effect on EGFR-overexpressing cancer cells, despite its smaller size and lower immunogenicity. This may be providing a basis for development of novel clinical therapeutic agents against EGFR-overexpressing tumor cells.	en_US
dc.language.iso	fa	en_US
dc.publisher	Tabriz University of Medical Sciences Faculty of Advanced Medical Science	en_US
dc.relation.isversionof	http://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/59559	en_US
dc.subject	E. coli	en_US
dc.subject	EGFR	en_US
dc.subject	Pseudomonas exotoxin	en_US
dc.subject	Immunotoxin	en_US
dc.subject	Humanized single chain antibody	en_US
dc.title	Preparation and evaluation of toxicity of anti-epidermal growth factor receptor (EGFR) immunotoxin containing truncated Pseudomonas aeruginosa exotoxin-A and humanized single chain fragment variable	en_US
dc.type	Thesis	en_US
dc.contributor.supervisor	Farajnia, Safar
dc.identifier.docno	160	en_US
dc.contributor.department	Medical Biotechnology	en_US
dc.description.discipline	Medical Biotechnology	en_US
dc.description.degree	Ph.D	en_US