The relationship between serum uricacid level and liver enzymes (ALT , AST ) and graft sonography and itima media sicknes (IMT) of fatty liver in patients with non-alcoholic fatty liver

Abstract

Introduction: Fatty liver disease that occurs in the absence of alcohol abuse is recognized as one of the main causes for the health of the community. Uric Acid is the ultimate purine metabolism that secretes in the urine, maintaining serum levels of uric acid with the balance between production and secretion. Purpose: Evaluation of the effects of increasing serum uric acid levels in non-alcoholic fatty liver. Methods: The study population was aged between 18-65 years old, and non-alcoholic fatty liver disease was confirmed by a specialist based on ultrasonographic results and clinical trials. People with chronic illness or drugs that affect the level of uric acid are consumed. Results: The level of uric acid has increased in the early months of the disease, and this indicator is also seen for AST and ALT, which in the early months of the disease has increased the level of the two enzymes and over time, the level of enzymes is reduced. There is a strong and significant association between the sixth month uricacid and the sixth month ALT and the sixth month AST. The results of the one way Anova test showed that uric acid had a significant difference with the levels of fatty liver in the 6th month. Conclusion: The amount of uric acid in people with non-alcoholic fatty liver increases and this increase in the early stages of the disease is more pronounced than the other stages of the disease, as well as between uric acid 6th and Grades 1, 2 and 3 of non-alcoholic fatty liver based on ultrasonography There is a meaningful relationship between the degree of non-alcoholic fatty liver and the degree of uric acid more than other grades.