Web-based simulation of plasma drug concentration: An educational tool for clinical pharmacokinetics

Abstract

The aim of present study was to develop an interactive web-based tool to teach medical students in clinical pharmacokinetics. The program was written in csharp (c#) language and its functionality was tested on Microsoft Internet Information Service (IIS) running on Microsoft Windows XP and, or Apache Web Server running on Linux Debian. Data of pharmacokinetic type was stored in a xml file, patient specific information such as plasma creatinine level, age, weight and gender are entered by student, some other data such as loading dose, maintenance dose and dosing interval are subject to the patient's physiological and pathological conditions are also judged by student and entered with the prior knowledge of specific drug and current selected patient's conditions. It is expected that this program should help students and other interested people to better understanding of clinical pharmacokinetics.