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dc.contributor.authorSaei, AA
dc.contributor.authorBarzegari, A
dc.date.accessioned2018-08-26T09:40:56Z
dc.date.available2018-08-26T09:40:56Z
dc.date.issued2012
dc.identifier.urihttp://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/58433
dc.description.abstractSpace medicine research has drawn immense attention toward provision of efficient life support systems during long-term missions into space. However, in extended missions, a wide range of diseases may affect astronauts. In space medicine research, the gastrointestinal microbiome and its role in maintaining astronauts health has received little attention. We would like to draw researchers attention to the significant role of microbiota. Because of the high number of microorganisms in the human body, man has been called a 'supra-organism and gastrointestinal flora has been referred to as 'a virtual organ of the human body. In space, the lifestyle, sterility of spaceship and environmental stresses can result in alterations in intestinal microbiota, which can lead to an impaired immunity and predispose astronauts to illness. This concern is heightened by increase in virulence of pathogens in microgravity. Thus, design of a personal probiotic kit is recommended to improve the health status of astronauts. © 2012 Future Medicine Ltd.
dc.language.isoEnglish
dc.relation.ispartofFuture Microbiology
dc.subjectimmunoglobulin A
dc.subjectprobiotic agent
dc.subjectadaptive immunity
dc.subjectaerospace medicine
dc.subjectantibody response
dc.subjectbacterial virulence
dc.subjectBifidobacterium bifidum
dc.subjectBifidobacterium breve
dc.subjectcosmonaut
dc.subjectdietary intake
dc.subjectdisease predisposition
dc.subjectenvironmental stress
dc.subjecthealth status
dc.subjecthuman
dc.subjectimmunity
dc.subjectinnate immunity
dc.subjectintestine flora
dc.subjectLactobacillus rhamnosus
dc.subjectlifestyle
dc.subjectmicrobiome
dc.subjectmicroflora
dc.subjectmicrogravity
dc.subjectnonhuman
dc.subjectpriority journal
dc.subjectreview
dc.subjectspace flight
dc.subjectAerospace Medicine
dc.subjectAnimals
dc.subjectAstronauts
dc.subjectBacteria
dc.subjectBacterial Infections
dc.subjectGastrointestinal Tract
dc.subjectHumans
dc.subjectInfant
dc.subjectMetagenome
dc.subjectMice
dc.subjectProbiotics
dc.subjectResearch
dc.subjectSpace Flight
dc.subjectWeightlessness
dc.titleThe microbiome: The forgotten organ of the astronauts body - Probiotics beyond terrestrial limits
dc.typeArticle
dc.citation.volume7
dc.citation.issue9
dc.citation.spage1037
dc.citation.epage1046
dc.citation.indexScopus
dc.identifier.DOIhttps://doi.org/10.2217/fmb.12.82


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