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dc.contributor.authorNiknazar, S
dc.contributor.authorFarajnia, S
dc.contributor.authorAsl, NA
dc.contributor.authorAlipur, MH
dc.contributor.authorNejad, LM
dc.contributor.authorRezaee, H
dc.date.accessioned2018-08-26T09:40:17Z
dc.date.available2018-08-26T09:40:17Z
dc.date.issued2008
dc.identifier10.3923/jbs.2008.1092.1095
dc.identifier.urihttp://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/58376
dc.description.abstractIn the present study, the effects of three months exercise training in the expression of ET-1 gene in lungs tissue were investigated. Twenty male Wistar rats (235آ±27 g) were maintamied on a 12:12 h light-dark cycle and received food and water. Animals were randomly divided into two groups (n = 10). Rats in test group ran on a treadmill for 60 min at a speed of 25 m min-1 daily for 3 months. Total RNA was extracted from the lung tissue and the expression of ET-1 mRNA was assessed by RT-PCR. Analysis of results indicated that the expression of ET-1 mRNA in the lung was significantly higher in the exercise rats than in the control rats (p<0.05). The results of this study were shown that three months exercise increased the ET-1 expression in the lungs that could increase the blood flow of lungs via ETB receptor. é 2008 Asian Network for Scientific Information.
dc.language.isoEnglish
dc.relation.ispartofJournal of Biological Sciences
dc.subjectbeta actin
dc.subjectendothelin 1
dc.subjectendothelin B receptor
dc.subjectRNA
dc.subjectanimal experiment
dc.subjectanimal model
dc.subjectanimal tissue
dc.subjectarticle
dc.subjectcontrolled study
dc.subjectexercise
dc.subjectfluid intake
dc.subjectfood intake
dc.subjectlight dark cycle
dc.subjectlung blood flow
dc.subjectlung parenchyma
dc.subjectmale
dc.subjectnonhuman
dc.subjectprotein expression
dc.subjectrat
dc.subjectreverse transcription polymerase chain reaction
dc.subjectRNA extraction
dc.subjecttreadmill exercise
dc.subjectvelocity
dc.subjectAnimalia
dc.subjectRattus
dc.subjectRattus norvegicus
dc.titleThe effects of three months exercise on expression of endothelin-1 in the lung tissue
dc.typeReview
dc.citation.volume8
dc.citation.issue6
dc.citation.spage1092
dc.citation.epage1095
dc.citation.indexScopus


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