The effect of varying levels of progesterone with fixed level of estrogen on concentrations of serum leptin in ovariectomized rats

Abstract

Sexual hormones especially estrogen have most effects on the fat tissues on the leptin's production. Changes of concentrations of progesterone in sexual cycles & hormonotrapies make changes in the exodic processes of estrogen's target systems. Aim of this study is the measurement of these effects on the changes of plasma leptin's levels. For the correct & complete analysis results we recorded other factors like insulin - Glc - HDL - LDL - TG & cholesterol. This research was done on the 56 female rats that have been divided into 7 groups of 8 rats. Then we did ovariectomy them 10 days before the starting test for the control of hormone levels. Hormone levels have controlled so that groups received constant estrogen with the different progesterone concentrations that we could measure the amounts of the effects of both hormones to each others.