The effect of small dose bupivacaine-fentanyl in spinal anesthesia on hemodynamic nausea and vomiting in cesarean section

Abstract

Objective: To compare the hemodynamic, nausea and vomiting with small dose bupivacaine-fentanyl spinal anesthetic versus a conventional dose of spinal bupivacaine in parturients undergoing cesarean section. Methodology: Forty patients aged 17-35 years old which underwent cesarean section were randomized into two groups. Group-A received spinal anesthesia with 8mg of bupivacaine and 10? g fentanyl, group B received 12mg bupivacaine. Results: The mean dose of ephedrine needed was 4mg in group A and 11.75mg in group B (P=0.006). The mean ratio of lowest systolic pressure to baseline systolic pressure was 0.75 for group A and 0.65 for group B (P=0.04). Nausea and vomiting was observed in 10% of group A versus 20% in group B. Conclusion: Small dose of bupivacaine and Fentanyl provides good spinal anesthesia for cesarean section with less hypotension, nausea and vomiting.