Supplementation with riboflavin (vitamin B2) for migraine prophylaxis in adults and children: A review
dc.contributor.author | Namazi, N | |
dc.contributor.author | Heshmati, J | |
dc.contributor.author | Tarighat-Esfanjani, A | |
dc.date.accessioned | 2018-08-26T09:36:56Z | |
dc.date.available | 2018-08-26T09:36:56Z | |
dc.date.issued | 2015 | |
dc.identifier.uri | http://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/58041 | |
dc.description.abstract | Background and Aim: Migraine is a unilateral and pulsating headache associated with nausea, photophobia, vomiting , and sensitivity to light. Low vitamin B2 can lead to mitochondrial dysfunction and may have an effect on migraine pathogenesis. The aim of the present study was to carry out a review of existing evidence regarding the effects of riboflavin (vitamin B2) supplementation on migraine prophylaxis in adults and children. Material and Methods: We searched the databases of PubMed, Science Direct, Google Scholar, and Springer between 1990 and December 2013. Key words included vitamin B2 , riboflavin, migraine, vomiting headache, and prevention. We limited our search to human studies in the English language. Review articles and abstracts from symposiums and conferences were excluded. Results: Finally, eleven eligible articles were found: seven involved studies with adults and four involved studies with children. The results indicated that supplementation with vitamin B2 in adults can play a positive role in reducing the frequency and duration of migraine attacks with no serious side effects. Conclusions: It seems that riboflavin is a safe and well-tolerated option for preventing migraine symptoms in adults, however, there is insufficient evidence to make recommendations regarding vitamin B2 as an adjunct therapy in adults and children with migraine. © 2015 Hans Huber Publishers. | |
dc.language.iso | English | |
dc.relation.ispartof | International Journal for Vitamin and Nutrition Research | |
dc.subject | placebo | |
dc.subject | riboflavin | |
dc.subject | riboflavin | |
dc.subject | adult disease | |
dc.subject | childhood disease | |
dc.subject | disease duration | |
dc.subject | human | |
dc.subject | meta analysis | |
dc.subject | migraine | |
dc.subject | randomized controlled trial (topic) | |
dc.subject | Review | |
dc.subject | systematic review | |
dc.subject | unspecified side effect | |
dc.subject | vitamin supplementation | |
dc.subject | adolescent | |
dc.subject | adult | |
dc.subject | aged | |
dc.subject | child | |
dc.subject | diet supplementation | |
dc.subject | middle aged | |
dc.subject | Migraine Disorders | |
dc.subject | preschool child | |
dc.subject | Adolescent | |
dc.subject | Adult | |
dc.subject | Aged | |
dc.subject | Child | |
dc.subject | Child, Preschool | |
dc.subject | Dietary Supplements | |
dc.subject | Humans | |
dc.subject | Middle Aged | |
dc.subject | Migraine Disorders | |
dc.subject | Riboflavin | |
dc.title | Supplementation with riboflavin (vitamin B2) for migraine prophylaxis in adults and children: A review | |
dc.type | Article | |
dc.citation.volume | 85 | |
dc.citation.issue | 1-2 | |
dc.citation.spage | 79 | |
dc.citation.epage | 87 | |
dc.citation.index | Scopus | |
dc.identifier.DOI | https://doi.org/10.1024/0300-9831/a000225 |
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