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dc.contributor.authorJouyban, A
dc.contributor.authorSajed-Amin, S
dc.contributor.authorPanahi-Azar, V
dc.date.accessioned2018-08-26T09:35:26Z
dc.date.available2018-08-26T09:35:26Z
dc.date.issued2014
dc.identifier.urihttp://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/57872
dc.description.abstractSolubilities of three drugs, i.e. atenolol, amiodarone HCl and lamotrigine in binary mixtures of polyethylene glycol 200 + water in the presence of beta-cyclodextrin (?-CD) along with the solubilities of atenolol and amiodarone HCl in this solvent mixture in the absence of ?-CD using saturating shake flask method were studied. The generated solubility data was fitted to the Jouyban-Aeree model and the solubility profile of each drug in the presence of ?-CD was compared with solubility data in the absence of ?-CD that the solubility data of lamotrigine taken from a previous paper.
dc.language.isoEnglish
dc.relation.ispartofJournal of Drug Delivery Science and Technology
dc.subjectamiodarone
dc.subjectatenolol
dc.subjectbeta cyclodextrin
dc.subjectlamotrigine
dc.subjectmacrogol 200
dc.subjectsolvent
dc.subjectwater
dc.subjectanalytic method
dc.subjectArticle
dc.subjectcomputer model
dc.subjectcontrolled study
dc.subjectdrug mixture
dc.subjectdrug solubility
dc.subjectdrug stability
dc.subjectdrug structure
dc.subjectmathematical model
dc.subjectshake flask method
dc.titleSolubility of atenolol, amiodarone HCl and lamotrigine in polyethylene glycol 200 + water mixtures in the presence of ?-cyclodextrin
dc.typeArticle
dc.citation.volume24
dc.citation.issue5
dc.citation.spage543
dc.citation.epage547
dc.citation.indexScopus
dc.identifier.DOIhttps://doi.org/10.1016/S1773-2247(14)50102-5


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