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Role of B cells in immune Tolerance

dc.contributor.authorArdalan, M
dc.date.accessioned2018-08-26T09:34:05Z
dc.date.available2018-08-26T09:34:05Z
dc.date.issued2012
dc.identifier.urihttp://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/57687
dc.description.abstractB cells are well known for their roles in antibody production, antigen presentation, modeling of the spleen architecture, and Th1/Th2 polarization of T cells. There is increasing evidence that some specific strains of B cells can also act as negative regulators and affect the development of graft tolerance. In certain experimental and clinical models, B-cell depletion has produced a time-dependent negative effect on the course of graft tolerance. In this article, we have discussed the implications of recent research on B-cell depletion therapy in transplantation. آ© 2012, Kowsar M.P.Co.
dc.language.isoEnglish
dc.relation.ispartofNephro-Urology Monthly
dc.subjectalloantibody
dc.subjectB cell activating factor
dc.subjectB cell maturation antigen
dc.subjectdaclizumab
dc.subjectinterleukin 10
dc.subjectrituximab
dc.subjectacute graft rejection
dc.subjectallergic encephalomyelitis
dc.subjectantibody affinity
dc.subjectantigen expression
dc.subjectarticle
dc.subjectB lymphocyte
dc.subjectB lymphocyte activation
dc.subjectcell maturation
dc.subjectcell selection
dc.subjectcell transplantation
dc.subjectchronic graft rejection
dc.subjectgraft recipient
dc.subjectgraft survival
dc.subjectHLA system
dc.subjecthuman
dc.subjectimmunological tolerance
dc.subjectkidney allograft
dc.subjectlymphocyte function
dc.subjectlymphocyte migration
dc.subjectlymphocyte subpopulation
dc.subjectlymphocyte transfer
dc.subjectlymphocytic infiltration
dc.subjectmultiple sclerosis
dc.subjectnonhuman
dc.subjectreceptor binding
dc.subjectrheumatoid arthritis
dc.subjectsignal transduction
dc.subjectsystemic lupus erythematosus
dc.subjecttransplantation tolerance
dc.titleRole of B cells in immune Tolerance
dc.typeArticle
dc.citation.volume4
dc.citation.issue1
dc.citation.spage336
dc.citation.epage339
dc.citation.indexScopus
dc.identifier.DOIhttps://doi.org/10.5812/kowsar. 22517006.1486


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