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Experimental determination and correlation of bosentan solubility in (PEG 200 + water) mixtures at T= (293.15-313.15) K

dc.contributor.authorBarzegar-Jalali, M
dc.contributor.authorMirheydari, SN
dc.contributor.authorRahimpour, E
dc.contributor.authorShekaari, H
dc.contributor.authorMartinez, F
dc.contributor.authorJouyban, A
dc.date.accessioned2018-08-26T08:55:02Z
dc.date.available2018-08-26T08:55:02Z
dc.date.issued2018
dc.identifier.urihttp://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/54240
dc.description.abstractThe solubility of bosentan (BST) in the aqueous mixtures of polyethylene glycol 200 (PEG 200) at the temperature range, Tآ =آ (293.15-313.15) K, has been studied using a shake-flask method. The experimental solubility data were correlated with Jouyban-Acree, Jouyban-Acree-van't Hoff, modified Wilson and Yalkowsky models. Deviations of the calculated solubility from experimental one were determined by percent average relative deviations and relative deviations. In addition, to represent the thermodynamic behaviour of BST in PEG 200 solutions, the apparent thermodynamic functions, Gibbs energy, enthalpy and entropy of dissolution were obtained by using the van't Hoff and Gibbs equations. é 2018 Informa UK Limited, trading as Taylor & Francis Group
dc.language.isoEnglish
dc.relation.ispartofPhysics and Chemistry of Liquids
dc.subjectMixtures
dc.subjectPolyethylene glycols
dc.subjectPolyethylenes
dc.subjectBinary solvent mixtures
dc.subjectBosentan
dc.subjectHoff equation
dc.subjectPolyethylene glycol 200
dc.subjectWilson model
dc.subjectSolubility
dc.titleExperimental determination and correlation of bosentan solubility in (PEG 200 + water) mixtures at T= (293.15-313.15) K
dc.typeArticle
dc.citation.spage1
dc.citation.epage12
dc.citation.indexScopus
dc.identifier.DOIhttps://doi.org/10.1080/00319104.2018.1491574


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