Effects of entonox in comparison with lidocaine on vital signs during episiotomy incision in nulliparous women: A randomized clinical trial

Abstract

Introduction: Delivery is potentially a stressful event. The maternal stress and anxiety, especially in the need for episiotomy, stimulates sympathetic system and leads to changes in vital signs which can have undesirable effects on maternal and fetal health. Therefore, this study was performed with aim to investigate the effects of entonox in comparison with lidocaine on vital signs during episiotomy incision in nulliparous women. Methods: This randomized clinical trial was performed on 120 nulliparous women in 215. Intervention group received entonox two minutes before starting episiotomy incision and its repair and was stopped at the end of the incision procedure. Control group as routine received 5 ml lidocaine 2% before starting incision episiotomy. Vital signs were evaluated and compared before and after incision and episiotomy by pulse oximeter. Data were analyzed by SPSS software (version 18) and Mann-Whitney and Chi-square tests. P<0.05 was considered significant. Resuts: There was no significant difference between pulse, oxygen saturation before and after of incision and repair of episiotomy, respiratory rate after of incision and before of repair episiotomy and systole and diastole blood pressure before and after of incision and repair of episiotomy (P>0.05). There was significant difference between two groups in terms of respiratory rate before incision and after of episiotomy repair (P<0.05). In entonox group, it was more than to lidocaine group. There was significant difference between diastolic blood pressure before and after incision (P<0.05); it was less in entonox group. No side effect was reported. Conclusion: Eentonox gas same as lidocaine when is used correctly has no adverse effects on mother's vital sign. © 2017, Mashhad University of Medical Sciences. All rights reserved.