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dc.contributor.authorPour, NH
dc.contributor.authorFarajollahi, A
dc.contributor.authorJamali, M
dc.contributor.authorZeinali, A
dc.contributor.authorJangjou, AG
dc.date.accessioned2018-08-26T08:51:04Z
dc.date.available2018-08-26T08:51:04Z
dc.date.issued2018
dc.identifier10.2478/pjmpe-2018-0004
dc.identifier.urihttp://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/53221
dc.description.abstractIntroduction: Due to the effect of radiation on both the tumor and the surrounding normal tissues, the side effects of radiation in normal tissues are expected. One of the important complications in the head and neck radiotherapy is the doses reached to the larynx and spinal cord of patients with non-laryngeal head and neck tumors. Materials and Methods: In this study, CT scan images of 25 patients with non-laryngeal tumors including; lymph nodes, tongue, oropharynx and nasopharynx were used. A three-field and a four-field treatment planning with and without laryngeal shield in 3D CRT technique were planned for each patient. Subsequently, the values of Dmin, Dmean, Dmax and Dose Volume Histogram from the treatment planning system and NTCP values of spinal cord and larynx were calculated with BIOPLAN and MATLAB software for all patients. Results: Statistical results showed that mean values of doses of larynx in both three and four-field methods were significantly different between with and without shield groups. Comparison of absorbed dose didn't show any difference between the three and four field methods (P>0.05). Using Shield, just the mean and minimum doses of spinal cord decreased in both three and four fields. The NTCP of the spinal cord and larynx by three and four-field methods with shield in the LKB and EUD models significantly are less than that of the three and four fields without shields, and in the four-field method NTCP of larynx is less than three radiation field. Conclusion: The results of this study indicate that there is no significant difference in doses reached to larynx and spinal cord between the treatments techniques, but laryngeal shield reduce dose and NTCP values in larynx considerably. آ© 2018 Noushin Hassan Pour et al., published by De Gruyter Open.
dc.language.isoEnglish
dc.relation.ispartofPolish Journal of Medical Physics and Engineering
dc.subjectArticle
dc.subjectcancer radiotherapy
dc.subjectclinical article
dc.subjectcomparative effectiveness
dc.subjectfemale
dc.subjectfour field radiotherapy
dc.subjecthead and neck tumor
dc.subjecthuman
dc.subjectlarynx edema
dc.subjectlymphoma
dc.subjectmale
dc.subjectnasopharynx tumor
dc.subjectoropharynx tumor
dc.subjectradiation dose
dc.subjectradiation field
dc.subjectthree field radiotherapy
dc.subjecttongue tumor
dc.subjectx-ray computed tomography
dc.titleComparison of three and four-field radiotherapy technique and the effect of laryngeal shield on vocal and spinal cord radiation dose in radiotherapy of non-laryngeal head and neck tumors
dc.typeArticle
dc.citation.volume24
dc.citation.issue1
dc.citation.spage25
dc.citation.epage31
dc.citation.indexScopus
dc.identifier.DOIhttps://doi.org/10.2478/pjmpe-2018-0004


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