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Bioactive lignans from the seeds of Centaurea macrocephala

dc.contributor.authorShoeb, M
dc.contributor.authorRahman, MM
dc.contributor.authorNahar, L
dc.contributor.authorDelazar, A
dc.contributor.authorJaspars, M
dc.contributor.authorMacmanus, SM
dc.contributor.authorSarker, SD
dc.date.accessioned2018-08-26T08:37:21Z
dc.date.available2018-08-26T08:37:21Z
dc.date.issued2004
dc.identifier.urihttp://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/52831
dc.description.abstractFour dibenzylbutyrolactone-type lignans, arctiin, lappaol A, matairesinol and matairesinoside were isolated from a methanol extract of the seeds of Centaurea macrocephala. The structures of these isolates were elucidated by spectroscopic means. The general toxicity and antioxidant activity of the isolated lignans were evaluated, respectively, by the brine shrimp lethality assay and the DPPH assay. The distribution of these lignans within the genus Centaurea has also been discussed.
dc.language.isoEnglish
dc.relation.ispartofDaru
dc.subjectarctiin
dc.subjectdibenzylbutyrolactone
dc.subjectlactone
dc.subjectlappaol a
dc.subjectlignan derivative
dc.subjectmatairesinol
dc.subjectmatairesinoside
dc.subjectunclassified drug
dc.subjectantioxidant activity
dc.subjectArtemia
dc.subjectarticle
dc.subjectcentaurea macrocephala
dc.subjectdrug isolation
dc.subjectevaluation
dc.subjectisolation procedure
dc.subjectlethality
dc.subjectnonhuman
dc.subjectplant seed
dc.subjectspectroscopy
dc.subjectstructure analysis
dc.subjectultraviolet spectroscopy
dc.titleBioactive lignans from the seeds of Centaurea macrocephala
dc.typeArticle
dc.citation.volume12
dc.citation.issue3
dc.citation.spage87
dc.citation.epage93
dc.citation.indexScopus


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