نمایش پرونده ساده آیتم

dc.contributor.authorRafeey, M
dc.contributor.authorKianrad, M
dc.contributor.authorHasani, A
dc.date.accessioned2018-08-26T08:36:49Z
dc.date.available2018-08-26T08:36:49Z
dc.date.issued2007
dc.identifier.urihttp://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/52782
dc.description.abstractObjective: To evaluate the clinical and para-clinical presentation, including autoantibody pattern, and response to treatment in Iranian children with autoimmune hepatitis (AIH). Methods: Data of 60 children presenting with AIH (56 girls) were analyzed retrospectively for clinical, serological and histological profile. Results: Clinical findings included jaundice (67%),hepatomegaly (50%) and ascites (30%). Forty children (38 girls) had type I AIH and 14 (12 girls) had type II AIH. Liver histology was comparable in the two groups and cirrhosis on initial biopsy was equally frequent in Types I and II AIH (63% vs 34%; p=ns). Conclusion: Our study describes the presentation and clinical course of Iranian children with AIH. Treatment with corticosteroids and/or azathioprine induces remission of autoimmune hepatitis clinically, biochemically as well as histologically. Copyright آ© 2007 by Indian Society of Gastroenterology.
dc.language.isoEnglish
dc.relation.ispartofIndian Journal of Gastroenterology
dc.subjectazathioprine
dc.subjectprednisolone
dc.subjectadolescent
dc.subjectarticle
dc.subjectascites
dc.subjectautoimmune hepatitis
dc.subjectchild
dc.subjectchronic liver disease
dc.subjectclinical feature
dc.subjectcombination chemotherapy
dc.subjectcontrolled study
dc.subjectdisease course
dc.subjectdrug dose reduction
dc.subjectdrug withdrawal
dc.subjectfemale
dc.subjecthepatomegaly
dc.subjecthuman
dc.subjecthuman tissue
dc.subjecthypergammaglobulinemia
dc.subjectIran
dc.subjectjaundice
dc.subjectliver biopsy
dc.subjectliver cirrhosis
dc.subjectliver disease
dc.subjectliver failure
dc.subjectliver histology
dc.subjectmagnetic resonance cholangiopancreatography
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectmonotherapy
dc.subjectphysical examination
dc.subjectrecurrent disease
dc.subjectunspecified side effect
dc.subjectAdolescent
dc.subjectAdrenal Cortex Hormones
dc.subjectAzathioprine
dc.subjectChild
dc.subjectChild, Preschool
dc.subjectFemale
dc.subjectHepatitis, Autoimmune
dc.subjectHumans
dc.subjectImmunosuppressive Agents
dc.subjectIran
dc.subjectMale
dc.subjectRetrospective Studies
dc.subjectTreatment Outcome
dc.titleAutoimmune hepatitis in Iranian children
dc.typeArticle
dc.citation.volume26
dc.citation.issue1
dc.citation.spage11
dc.citation.epage13
dc.citation.indexScopus


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