Autoimmune hepatitis in Iranian children
dc.contributor.author | Rafeey, M | |
dc.contributor.author | Kianrad, M | |
dc.contributor.author | Hasani, A | |
dc.date.accessioned | 2018-08-26T08:36:49Z | |
dc.date.available | 2018-08-26T08:36:49Z | |
dc.date.issued | 2007 | |
dc.identifier.uri | http://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/52782 | |
dc.description.abstract | Objective: To evaluate the clinical and para-clinical presentation, including autoantibody pattern, and response to treatment in Iranian children with autoimmune hepatitis (AIH). Methods: Data of 60 children presenting with AIH (56 girls) were analyzed retrospectively for clinical, serological and histological profile. Results: Clinical findings included jaundice (67%),hepatomegaly (50%) and ascites (30%). Forty children (38 girls) had type I AIH and 14 (12 girls) had type II AIH. Liver histology was comparable in the two groups and cirrhosis on initial biopsy was equally frequent in Types I and II AIH (63% vs 34%; p=ns). Conclusion: Our study describes the presentation and clinical course of Iranian children with AIH. Treatment with corticosteroids and/or azathioprine induces remission of autoimmune hepatitis clinically, biochemically as well as histologically. Copyright آ© 2007 by Indian Society of Gastroenterology. | |
dc.language.iso | English | |
dc.relation.ispartof | Indian Journal of Gastroenterology | |
dc.subject | azathioprine | |
dc.subject | prednisolone | |
dc.subject | adolescent | |
dc.subject | article | |
dc.subject | ascites | |
dc.subject | autoimmune hepatitis | |
dc.subject | child | |
dc.subject | chronic liver disease | |
dc.subject | clinical feature | |
dc.subject | combination chemotherapy | |
dc.subject | controlled study | |
dc.subject | disease course | |
dc.subject | drug dose reduction | |
dc.subject | drug withdrawal | |
dc.subject | female | |
dc.subject | hepatomegaly | |
dc.subject | human | |
dc.subject | human tissue | |
dc.subject | hypergammaglobulinemia | |
dc.subject | Iran | |
dc.subject | jaundice | |
dc.subject | liver biopsy | |
dc.subject | liver cirrhosis | |
dc.subject | liver disease | |
dc.subject | liver failure | |
dc.subject | liver histology | |
dc.subject | magnetic resonance cholangiopancreatography | |
dc.subject | major clinical study | |
dc.subject | male | |
dc.subject | monotherapy | |
dc.subject | physical examination | |
dc.subject | recurrent disease | |
dc.subject | unspecified side effect | |
dc.subject | Adolescent | |
dc.subject | Adrenal Cortex Hormones | |
dc.subject | Azathioprine | |
dc.subject | Child | |
dc.subject | Child, Preschool | |
dc.subject | Female | |
dc.subject | Hepatitis, Autoimmune | |
dc.subject | Humans | |
dc.subject | Immunosuppressive Agents | |
dc.subject | Iran | |
dc.subject | Male | |
dc.subject | Retrospective Studies | |
dc.subject | Treatment Outcome | |
dc.title | Autoimmune hepatitis in Iranian children | |
dc.type | Article | |
dc.citation.volume | 26 | |
dc.citation.issue | 1 | |
dc.citation.spage | 11 | |
dc.citation.epage | 13 | |
dc.citation.index | Scopus |
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