| dc.description.abstract | Introduction: Acinetobacter species are one of important causes of nosocomial infections in many hospitals. The aim of this study is to evaluate the incidence of acinetobacter infection and identifying pattern of antibiotical susceptibility in different species of acinetobacter in Sina hospital. Methods: In a analytic cross sectional study all patients hospitalized from year 2000 to year 2008 were studied. Study population was those with isolated acinetobacter from blood, urine, respiratory tract discharges, sputum, wound discharges and burnings after 48 hours of hospitalization. Then, antimicrobial susceptibility tests were done on acinetobacter isolates. Results: Resistance rate to aminoglycosides, third generation cephalosporins and quinolones were high in years 2006, 2007 and 2008 respectively. Burning and surgery ICU wards had the most isolation of acintobacters. Resistance rate to carbapenems were 25% in year 2005, 37.5% in year 2007 and 64.7% in year 2008. Isolation of acintobacters was mainly from the burning wounds, respiratory tract discharges, blood, wounds, urine or Foley catheter. Conclusion: According to multi drug resistance of acintobacters, physicians usually face problems in controlling the nosocomial infections due to this organism. Complete resistance of acinetobacter to third generation cephalosporins and quinolones and increasing resistance to aminoglycosides are indicative of inappropriate use of these types of antibiotics in this period. If we did not avoid administering antibiotics none principally, soon should expect complete resistance to other types of antibiotics certainly carbapenems. | |
